Citrulline is an amino acid that is turned into L-arginine in the kidneys after supplementation, L-Citrulline anti-depressant effects still need clinical validation. This means that L-citrulline supplementation is a more effective method of increasing L-arginine levels in the body than L-arginine supplementation itself. L-Citrulline is one of the three dietary amino acids in the urea cycle. Others …